Using a beam of helium ions as the imaging particles, higher resolution and greater detailed images can be generated because ions can be focused into a smaller probe size and have less sample interaction than electron beam instruments. For more information.
Using a combination of SIMS and AFM,
researchers are closer to the goal of describing
the complexity of membrane organization
with high spatial resolution and a high
degree of chemical information. Research Highlights, Nature Methods, vol 3. No.12 p. 962-963.
New microscope tips use capillary action to print patterns tens of nanometers across. From NSF
Describes a technique in an AFM that allows recognition of a specific type of molecule in a complex sample (chromatin) while simultaneously yielding high-resolution topographic images. C. Stroh et al., PNAS, 2004, vol. 101, no. 34
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