Microscopy Web Resources and News

Advanced Light Microscopy Resources on the Web


Fluorescence Microscopy

Pushing the Envelope in Biological Imaging

Eric Betzig develops novel optical imaging tools in an effort to open new windows into molecular, cellular, and neurobiology.

Single-molecule biology and Bioimaging Zhuang Research Lab

Zhuang Lab at Harvard University is developing real-time fluorescence imaging methods to track the behavior of single virus particles and of single viral genomes in live cells.

Fluorescence microscopy with super-resolved optical sections

Alexander Egner1 and Stefan W. Hell, TRENDS in Cell Biology Vol.15 No.4 April 2005

Shattering the diffraction limit of light: A revolution in fluorescence microscopy?

Sharper Image

An overview of the development of the the Palm

High Resolution Light Microscopy of Live Cells

Microscopy Today, V. Vodyanoy, June 2005

Squint Busters

October 2006 article on microscopes that are pushing resolution to single-molecule sharpness.

Blinded by the Light

Published in 2004, the article reviews advances in light microscopy including 4Pi, STED, confocal imaging, and total internal reflection fluorescence.

New Innovations for Biological Imaging and Instrumentation at HHMI

The Applied Physics and Instrumentation Group (APIG) at Janelia Farms seeks to understand bioimaging challenges and to harness new technologies for advanced imaging. Three initial projects will characterize this effort: higher resolution novel microscopy, high-throughput microscopy, and correlative microscopy.

Super-Resolution Microscopy Captures Molecules in Motion

A new twist on a sophisticated light microscopy technique is enabling researchers to capture short videos of fast-moving cellular processes while delivering super high resolution images of whole cells.

Nonlinear structured-illumination microscopy:

Technical details on structured-illumination microscopy.

A New Approach to Fluorescence Microscopy

GE & Science Prize for Young Life Scientists winning essay by Mark Bates describing his discovery of a new type of “optically switchable” fluorescent molecule, and how these molecules were used for high-resolution biological imaging.