Learn about the science underlying public health issues by perusing -- and using -- digitized images on view.
This well done site includes principles of virus structure, Electron Microscopy:How images are created by negative staining, electron microscopy images, and lecture notes.
James Hillier OC (August 22, 1915 – January 15, 2007) was a Canadian-born scientist and inventor who designed and built, with Albert Prebus, the first successful high-resolution electron microscope in North America in 1938.
Keith Roberts Porter (1912-1997) was a Canadian cell biologist. He did pioneering biology research using electron microscopy of cells [1], such as work on the 9 + 2 microtubule structure in the axoneme of cilia.
In the early 1950s, Palade’s utilization of the then new technologies, such as electron microscopy and ultracentrifugation,brought understanding of the cell to a new level.
This autobiography/biography was written at the time of the award and later published in the book series Les Prix Nobel/Nobel Lectures.
National Inventors Hall of Fame ™
The collection includes some of the earliest electron micrographs from Rockefeller University and Yale University. Many of the images are significant for their contribution to our understanding of cellular structure and processes. The images were used in the cell biology courses at Yale University by Drs. George Palade and Marilyn Farquhar. It was Dr. Palade's wish that the collection of images be freely available to students and scientists world-wide.
Scanning and transmission electron microscope images from FEI company.
Introduction to the Transmission Electron Microscope.
The transmission electron microscope uses principles that originated in light microscopy and which therefore rely on the properties of waves. These principles are illustrated.
Brief introduction to the Principle and application of Imaging electron energy loss spectroscopy
Introduction to the Dynamic Transmission Electron Microscope (DTEM) at Lawrence Livermore Laboratories that provides the ability to image transient behaviors such as how a chemical reaction, structural deformation or phase transformation takes place with an unprecedented combination of spatial and temporal resolution: nanometers and nanoseconds.
Read the FEI booklet "An Introduction to Electron Microscopy", an excellent resource on electron microscopy and nanotechnology for students and teachers
For biological and material scientists who are new to TEM, but need to learn to use the technique.
Current course notes for electron microscopy in pdf and Powerpoint. The <em>Bottom Line</em> is especailly helpful and focuses basic concepts that are important for understanding the fundamental principles of transmission electron microscopy, biological specimen preparation, and three-dimensional image processing and reconstruction. Winter 2011 course is 3D Electron Microscopy of Macromolecules.
This is a set of resources designed to accompany an introductory course on transmission electron microscopy. The level is appropriate for students with an understanding of some elementary physics.
Learn to use a transmission electron microscope...fast. This site has put together by John Rodenburg, who has been teaching graduate students to use TEMs for over twenty years (at the University of Cambridge, Sheffield Hallam and Sheffield Universities). Now includes a new section on TEM/STEM alignment.
Cource notes, protocols, and power point presentation for specimen preparation for scanning electron and transmission electon microscopy and overviews of instrumentation.
Complete course notes.
The history and overview section provides an introduction to STEM.
Overview of the advances in transmission electron microscopes atomic level imaging and elemental analysis that move the TEM into the realm of analytical chemistry.
Fluctuation microscopy has been used to study disordered materials including amorphous Ge and silicon. This paper is a general introduction to the technique.
The Royal Swedish Academy of Sciences has decided to award the 1986 Nobel Prize in Physics by one half to Professor. Ernst Ruska, Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Federal Republic of Germany, for his fundamental work in electron optics, and for the design of the first electron microscope and the other half, jointly to Dr Gerd Binnig and Dr Heinrich Rohrer, IBM Research Laboratory, Zurich, Switzerland, for their design of the scanning tunnelling microscope.
George E. Palade – Nobel Lecture, December 12, 1974
History of electron microscopy at Rockefeller University and the
A complete listing of the publications of James Hillier who designed the first mass produced instrument and invented many techniques that extended the application of the electron microscope to a broad spectrum of sciences. Copies of many of the following are available from the Foundation for a nominal fee.
The unique two-year program in Microscopy is offered to those students who, upon graduation, wish to find employment as technical support persons operating microscopes, doing sample preparation and interpretation, or in technical sales and marketing.
The Electron Microscopy program is a two-year program in which students learn to operate electron microscopes and related equipment, both scanning (SEM) and transmission (TEM). The program includes preparation of biological and material samples, communication skills, computer-image processing, X-ray microanalysis, and maintenance of electron microscopes and related equipment.