Microscopy Web Resources and News

Electron Microscope Sample Preparation Resources on the Web


Microscope Manuals

The Diatome Handling and Use Manual: Technical Information

Includes information on diamond knives for cryo-ultramicrotomy, low angle diamond knives, as well as knives for light microscopy and histology.

Technical Overviews of Microscopes and Microscopy

TEM Sample Preparation Guide

Preparation for Transmission Electron Microscopy (TEM) guide in English and French includes thinning, cleaving, polishing, and replicating of materials as well as ultramicrotomy and tissue staining.

Protocols and Procedures Used in Microscopy

Microwave Sample Preparation

The sharing of methodology and protocols for microwave-assisted sample preparation, immunolabeling, decalcification and other applications

Applications, Techniques, and Protocols

Product and technical information. The technical information includes papers MMA embedding and staining procedures.

Electron Microscopy Sciences Technical Data Sheets

A collection of almost 100 information sheets for a wide variety of EM plastic resins, fixatives, and other products used in sample preparation.

TEM specimen preparation and immunolabelling

These pages contain information on light microscopy, transmission electron microcopes, cryosectioning, immunocytochemistry and other imaging techniques used in modern biomedical research.

Basic Preparation of Insect Specimens for SEM

Laboratory Methods

Tissue fixation, staining, and embedding for transmission electron microscopy.

EM Lab manual

Laboratory manual with protocols for TEM and SEM preparation. Also includes instructions on operation of in house equipment.

Peer Reviewed Article

A Study of Fixation for Electron Microscopy

article describe the first use of osmium tetoxide as a tissue fixative for transmission electron microscopy.